Mary-Claire King

Mary-Claire King

玛丽-克莱尔·金

b. 1946美国遗传学与生物技术

Discovered the BRCA1 Cancer Gene

Biography

Mary-Claire King proved that breast cancer can be inherited through a single gene — BRCA1 — revolutionizing cancer research and prevention. Her discovery, made in 1990 after 17 years of research, enabled genetic testing that has saved countless lives through early detection. She also proved that humans and chimpanzees are 99% genetically identical and used DNA analysis to identify victims of Argentina's 'Dirty War,' reuniting stolen children with their biological families.

玛丽-克莱尔·金证明了乳腺癌可以通过单一基因——BRCA1——遗传,革新了癌症研究和预防。她的发现是在17年研究之后于1990年做出的,使基因检测成为可能,通过早期检测挽救了无数生命。她还证明人类和黑猩猩在基因上有99%相同,并利用DNA分析鉴定阿根廷'肮脏战争'的受害者,帮助被盗儿童与亲生家庭团聚。

Key Achievements

  • Discovered BRCA1 breast cancer gene

    发现BRCA1乳腺癌基因

  • Proved 99% genetic similarity between humans and chimps

    证明人类和黑猩猩99%基因相似

  • Used DNA to identify victims of Argentina's Dirty War

    利用DNA鉴定阿根廷肮脏战争受害者

References & Citations

  1. Wikipedia: Mary-Claire King — https://en.wikipedia.org/wiki/Mary-Claire_King
  2. King, M.C. et al. 'Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2,' Science, 2003.