Nancy Wexler

Biography

Nancy Wexler is a neuropsychologist who led the international effort to locate the gene responsible for Huntington's disease. Her groundbreaking research with a large Venezuelan kindred near Lake Maracaibo was crucial to mapping the gene to chromosome 4 in 1983 and ultimately identifying it in 1993. Her quest was deeply personal — her own mother died of Huntington's disease. As president of the Hereditary Disease Foundation, she has dedicated her career to understanding and combating hereditary diseases.

南希·韦克斯勒是一位神经心理学家，领导了定位亨廷顿病致病基因的国际研究。她对委内瑞拉马拉开波湖附近一个大家族的开创性研究，对1983年将该基因定位到第4号染色体以及1993年最终鉴定该基因起到了关键作用。她的探索有着深刻的个人原因——她的母亲死于亨廷顿病。作为遗传性疾病基金会主席，她毕生致力于理解和对抗遗传性疾病。

Key Achievements

• Led effort to locate the Huntington's disease gene

  领导定位亨廷顿病基因的研究

• Research crucial to mapping gene to chromosome 4 (1983)

  研究对将基因定位到第4号染色体起关键作用（1983年）

• President of the Hereditary Disease Foundation

  遗传性疾病基金会主席

References & Citations

1. Wikipedia: Nancy Wexler — https://en.wikipedia.org/wiki/Nancy_Wexler
2. Wexler, A. Mapping Fate: A Memoir of Family, Risk, and Genetic Research. University of California Press, 1996.